Over the last few years, SOCO has achieved some advances in the theory and application of Supervised Neural Network models, including studies on activation functions, heterogeneous neurons, Bayesian techniques, Recurrent Networks, sequential construction of Neural Networks and the proposal of a methodology for Feature Selection with Multilayer Perceptrons, based on the Sequential Backward Selection procedure.
The first five describe methodologies with a similar goal: the resolution of complex problems that cannot be efficiently solved by means of traditional computational methods (hard computing). Feature Selection and Extraction deals with problems of data dimensionality reduction that are present in all the previous lines. Finally, Pattern Recognition and Computer Vision copes with a huge application field where the performance of AI systems is usually worse than the human one, and where the soft computing techniques have great potential. Related to it, Data and Knowledge Visualization concerns ways in which Soft Computing complements human vision in problems of exploratory Data Mining.
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SOCO's current main line of research is in the areas of biomedicine and bioinformatics. Our work involves the development of robust Computational Intelligence techniques and their application to data-based medical diagnosis and prognosis, mainly in the area of neuro-oncology, and to protein sequence analysis for pharmaco-proteomics. In the former problem, SOCO collaborates with the Neural Computation Research Group [go] at Liverpool John Moores University [go] in U.K., and with the Grup d'Aplicacions Biomèdiques de la Ressonància Magnètica Nuclear (GABRMN) [go] at Universitat Autònoma de Barcelona (UAB) [go]. In the latter problem, SOCO is currently leading a MINECO R+D project (TIN2012-31377), titled "KAPPA AIM: Knowledge Acquisition in Pharmacoproteomics using Advanced Artificial Intelligence Methods", in collaboration with the Systems Pharmacology and Bioinformatics group [go] at UAB. SOCO also collaborates in the SHOCKOMICS European project [go] providing data science in a multiscale approach to the identification of molecular biomakers in acute heart failure induced by shock. We also investigate major depressive disorders. The prevalence of depression, its social and personal costs and its recurrent characteristics, put heavy constraints on the ability of public healthcare systems to provide sufficient support for patients with depression. Current research at SOCO includes the design and development of a remote intelligent monitoring and prediction system that performs an automatic assessment on the progress of the patient in a short-term basis, carrying out prediction of possible reoccurrence or relapses.
SOCO also collaborated with the Servei de Medicina Interna de l'Hospital General de la Vall d'Hebron [go] in a study of the relevance of several clinical and immunological variables for the prediction of cancer in patients with idiopathic inflammatory myopathies.